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KMID : 0360220120530071002
Journal of the Korean Ophthalmological Society
2012 Volume.53 No. 7 p.1002 ~ p.1010
Correlation Between Central Corneal Thickness and Glaucomatous Damage
Kim Yoon-Jeon

Na Jung-Hwa
Lee Young-Rok
Sung Kyung-Rim
Abstract
Purpose: To evaluate the correlations between central corneal thickness (CCT) and optic disc and retinal nerve fiber layer (RNFL) parameters determined by spectral domain optical coherence tomography (SD OCT) and visual field (VF) global indices.

Methods: The present study included 151 eyes diagnosed with open-angle glaucoma (OAG) and 135 glaucoma suspect (GS) eyes. The CCT, RNFL thickness, optic disc parameters, and VF global indices were measured. The relationships between CCT and RNFL thickness, optic disc parameters, and VF global indices were assessed by linear regression analysis.

Results: Intraocular pressure (IOP, p < 0.001) and VF mean deviation (p = 0.005) in all participants, age (p = 0.017) and IOP (p = 0.003) in the GS group, and IOP (p = 0.002) and inferior RNFL thickness (p = 0.017) in the OAG group were significantly associated with CCT. Among the optic disc parameters, rim area, average cup/disc ratio, and vertical cup/disc ratio were significantly associated with CCT in all participants in the univariate but not multivariate analysis.

Conclusions: Optic disc parameters obtained by SD OCT were not correlated with CCT in the OAG or GS group, while RNFL thickness and VF mean deviation showed associations.
KEYWORD
Central corneal thickness, Optic disc parameters, Retinal nerve fiber layer thickness, Spectral domain optical coherence tomography, Visual field indices
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